Complementation of a methotrexate uptake defect in Chinese hamster ovary cells by DNA-mediated gene transfer.
A methotrexate-resistant Chinese hamster ovary cell line deficient in methotrexate uptake has been complemented to methotrexate sensitivity by transfection with DNA isolated from either wild-type Chinese hamster ovary or human G2 cells. Primary and secondary transfectants regained the ability to tak...
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| Published in: | Mol Cell Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
1989
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362594/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2725523/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.4.1754-1758.1989 |
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