pp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src.

In previous studies examining the potential role of pp60c-src in cellular proliferation, we demonstrated that C3H10T1/2 murine embryo fibroblasts overexpressing transfected chicken genomic c-src displayed an epidermal growth factor (EGF)-induced mitogenic response which was 200 to 500% of the respon...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Wilson, L K, Luttrell, D K, Parsons, J T, Parsons, S J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362570/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2471064/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.4.1536-1544.1989
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