Rapid Sequential Injections of Hyperpolarized [1-(13)C]Pyruvate In Vivo Using a Sub-Kelvin, Multi-Sample DNP Polarizer

The development of hyperpolarized technology utilizing dynamic nuclear polarization (DNP) has enabled the rapid measurement of (13)C metabolism in vivo with very high SNR. However, with traditional DNP equipment, consecutive injections of a hyperpolarized compound in an animal have been subject to a...

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Bibliographic Details
Main Authors: Hu, Simon, Larson, Peder E.Z., VanCriekinge, Mark, Leach, Andrew M., Park, Ilwoo, Leon, Christine, Zhou, Jenny, Shin, Peter J., Reed, Galen, Keselman, Paul, von Morze, Cornelius, Yoshihara, Hikari, Bok, Robert A., Nelson, Sarah J., Kurhanewicz, John, Vigneron, Daniel B.
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625683/
https://ncbi.nlm.nih.gov/pubmed/23107275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mri.2012.09.002
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