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Down-regulation of Pdcd4 leads to epithelial to mesenchymal transition and promotes metastasis in mice
In this study, we demonstrated that knockdown of Programmed cell death 4 (Pdcd4), a novel tumor suppressor, decreased the expressions of epithelial-specific proteins and increased the expressions of mesenchymal-specific proteins in vitro and in vivo, suggesting that knockdown of Pdcd4 results in epi...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3625476/ https://ncbi.nlm.nih.gov/pubmed/23312883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2012.12.014 |
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