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Toward the Treatment and Prevention of Alzheimer’s Disease: Rational Strategies and Recent Progress
Alzheimer’s disease (AD) is the major cause of late-life brain failure. In the past 25 years, autosomal dominant forms of AD were found to be primariy attributable to mutations in one of two presenilins, polytopic proteins that contain the catalytic site of the γ-secretase protease that releases the...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3625402/ https://ncbi.nlm.nih.gov/pubmed/23327526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-med-092611-084441 |
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