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Substrate selectivity in glutamate-dependent acid resistance in enteric bacteria

The bacterial antiporter GadC plays a central role in the glutamate (Glu)-dependent acid resistance system, which protects enteric bacteria against the extreme acidity of the human stomach. Upon acid shock, GadC imports Glu into the cytoplasm, where Glu decarboxylases consume a cytoplasmic proton, w...

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Autori principali: Tsai, Ming-Feng, McCarthy, Patrick, Miller, Christopher
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625338/
https://ncbi.nlm.nih.gov/pubmed/23530225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301444110
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