Targeting complement component 5a promotes vascular integrity and limits airway remodeling

Increased microvascular dilatation and permeability is observed during allograft rejection. Because vascular integrity is an important indicator of transplant health, we have sought to limit injury to blood vessels by blocking complement activation. Although complement component 3 (C3) inhibition is...

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Detalhes bibliográficos
Main Authors: Khan, Mohammad A., Maasch, Christian, Vater, Axel, Klussmann, Sven, Morser, John, Leung, Lawrence L., Atkinson, Carl, Tomlinson, Stephen, Heeger, Peter S., Nicolls, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625314/
https://ncbi.nlm.nih.gov/pubmed/23530212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217991110
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