Structure-Function-Immunogenicity Studies of PfEMP1 Domain DBL2β(PF11_0521), a Malaria Parasite Ligand for ICAM-1

Plasmodium falciparum virulence has been ascribed to its ability to sequester in deep vascular beds, mediated by the variant surface antigen family PfEMP1 binding endothelial receptors like ICAM-1. We previously observed that naturally-acquired antibodies that block a PfEMP1 domain, DBL2β of PF11_05...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gullingsrud, Justin, Saveria, Tracy, Amos, Emily, Duffy, Patrick E., Oleinikov, Andrew V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625211/
https://ncbi.nlm.nih.gov/pubmed/23593462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061323
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