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Autophagy contributes to lysosomal storage disorders

Degradation in the lysosome/vacuole is not the final step of autophagy. In particular, for starvation-induced autophagy it is necessary to release the breakdown products back into the cytosol. However, some researchers ignore this last step and simply refer to the endpoint of autophagy as degradatio...

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Bibliographic Details
Main Authors: Shimada, Yohta, Klionsky, Daniel J.
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625119/
https://ncbi.nlm.nih.gov/pubmed/22617443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.19920
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