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Tissue-specific transcription of the mouse alpha-fetoprotein gene promoter is dependent on HNF-1.

Previous work identified four upstream cis-acting elements required for tissue-specific expression of the alpha-fetoprotein (AFP) gene: three distal enhancers and a promoter. To further define the role of the promoter in regulating AFP gene expression, segments of the region were tested for the abil...

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Bibliographic Details
Main Authors: Feuerman, M H, Godbout, R, Ingram, R S, Tilghman, S M
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC362499/
https://ncbi.nlm.nih.gov/pubmed/2479822
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