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Mining Gold Dust under the Genome Wide Significance Level: A Two-Stage Approach to Analysis of GWAS

We propose a two-stage approach to analyze genome-wide association (GWA) data in order to identify a set of promising single-nucleotide polymorphisms (SNPs). In stage one, we select a list of top signals from single SNP analyses by controlling false discovery rate (FDR). In stage two, we use the lea...

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Autori principali: Shi, Gang, Boerwinkle, Eric, Morrison, Alanna C., Gu, C. Charles, Chakravarti, Aravinda, Rao, DC
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624896/
https://ncbi.nlm.nih.gov/pubmed/21254218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20556
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