Repeated in vivo exposure of cocaine induces long-lasting synaptic plasticity in hypocretin/orexin-producing neurons in the lateral hypothalamus in mice

Hypocretin (orexin), a neuropeptide synthesized exclusively in the perifornical/lateral hypothalamus, is critical for drug seeking and relapse, but it is not clear how the circuitry centred on hypocretin-producing neurons (hypocretin neurons) is modified by drugs of abuse and how changes in this cir...

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Detalhes bibliográficos
Main Authors: Rao, Yan, Mineur, Yann S, Gan, Geliang, Wang, Alex Hanxiang, Liu, Zhong-Wu, Wu, Xinyuan, Suyama, Shigetomo, de Lecea, Luis, Horvath, Tamas L, Picciotto, Marina R, Gao, Xiao-Bing
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Neuroscience: Behavioural/Systems/Cognitive
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624862/
https://ncbi.nlm.nih.gov/pubmed/23318871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.246983
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