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Genetically encoded pH-indicators reveal activity-dependent cytosolic acidification of Drosophila motor nerve termini in vivo

All biochemical processes, including those underlying synaptic function and plasticity, are pH sensitive. Cytosolic pH (pH(cyto)) shifts are known to accompany nerve activity in situ, but technological limitations have prevented characterization of such shifts in vivo. Genetically encoded pH-indicat...

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Autori principali: Rossano, Adam J, Chouhan, Amit K, Macleod, Gregory T
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624846/
https://ncbi.nlm.nih.gov/pubmed/23401611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.248377
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