The CUP2 gene product, regulator of yeast metallothionein expression, is a copper-activated DNA-binding protein.

CUP2 is a regulatory gene controlling expression of CUP1, which encodes the Cu-binding yeast metallothionein. CUP2, which is identical to the ACE1 gene, encodes a Cu-regulated DNA-binding protein. The CUP2 protein contains a cysteine-rich DNA-binding domain dependent on Cu+ and Ag+ ions which bind t...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Buchman, C, Skroch, P, Welch, J, Fogel, S, Karin, M
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 1989
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362479/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2674688/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.9.4091-4095.1989
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