The mouse thymidylate synthase promoter: essential elements are in close proximity to the transcriptional initiation sites.

The promoter region of the mouse thymidylate synthase gene was analyzed by deletion and site-directed mutagenesis. Elimination of an upstream Sp1 element reduced expression threefold, whereas elimination of an adenovirus upstream stimulatory factor element had little effect. All of the upstream elem...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Deng, T, Li, Y, Jolliff, K, Johnson, L F
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1989
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362476/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2779579/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.9.4079-4082.1989
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