Temporal Transcriptional Response during Infection of Type II Alveolar Epithelial Cells with Francisella tularensis Live Vaccine Strain (LVS) Supports a General Host Suppression and Bacterial Uptake by Macropinocytosis

Pneumonic tularemia is caused by inhalation of Francisella tularensis, one of the most infectious microbes known. We wanted to study the kinetics of the initial and early interactions between bacterium and host cells in the lung. To do this, we examined the infection of A549 airway epithelial cells...

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Detalhes bibliográficos
Main Authors: Bradburne, Christopher E., Verhoeven, Anne B., Manyam, Ganiraju C., Chaudhry, Saira A., Chang, Eddie L., Thach, Dzung C., Bailey, Charles L., van Hoek, Monique L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Genomics and Proteomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624459/
https://ncbi.nlm.nih.gov/pubmed/23322778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.362178
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