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Calcium, Bioenergetics, and Neuronal Vulnerability in Parkinson's Disease
The most distinguishing feature of neurons is their capacity for regenerative electrical activity. This activity imposes a significant mitochondrial burden, especially in neurons that are autonomously active, have broad action potentials, and exhibit prominent Ca(2+) entry. Many of the genetic mutat...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3624453/ https://ncbi.nlm.nih.gov/pubmed/23086948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R112.410530 |
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