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An RNA Element in Human Interleukin 6 Confers Escape from Degradation by the Gammaherpesvirus SOX Protein

Several viruses express factors to silence host gene expression via widespread mRNA degradation. This phenotype is the result of the coordinated activity of the viral endonuclease SOX and the cellular RNA degradation enzyme Xrn1 during lytic Kaposi's sarcoma-associated herpesvirus (KSHV) infect...

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Detalhes bibliográficos
Main Authors: Hutin, Stephanie, Lee, Yeon, Glaunsinger, Britt A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624381/
https://ncbi.nlm.nih.gov/pubmed/23408619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00159-13
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