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Variation of HIV-1 Mutation Spectra among Cell Types

The high rates of mutation, recombination, and replication drive HIV-1 diversity. In this study, we investigated how cell type affects viral mutation rate and mutation spectra. In studying four different cell types, no differences in mutation rate were observed, but intriguingly cell type difference...

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Detalhes bibliográficos
Main Authors: Holtz, Colleen M., Mansky, Louis M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624292/
https://ncbi.nlm.nih.gov/pubmed/23449788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03576-12
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