Genetic Screen of a Mutant Poxvirus Library Identifies an Ankyrin Repeat Protein Involved in Blocking Induction of Avian Type I Interferon

Mammalian poxviruses, including vaccinia virus (VACV), have evolved multiple mechanisms to evade the host type I interferon (IFN) responses at different levels, with viral proteins targeting IFN induction, signaling, and antiviral effector functions. Avian poxviruses (avipoxviruses), which have been...

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Detalhes bibliográficos
Main Authors: Laidlaw, Stephen M., Robey, Rebecca, Davies, Marc, Giotis, Efstathios S., Ross, Craig, Buttigieg, Karen, Goodbourn, Stephen, Skinner, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624286/
https://ncbi.nlm.nih.gov/pubmed/23427153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02736-12
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