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Identification of a Hydrophobic Domain in Varicella-Zoster Virus ORF61 Necessary for ORF61 Self-Interaction, Viral Replication, and Skin Pathogenesis

The varicella-zoster virus (VZV) ORF61 protein is necessary for normal replication in vitro and virulence in human skin xenografts in the severe combined immunodeficiency mouse model in vivo. These experiments identify a hydrophobic domain that mediates ORF61 self-interaction. While not needed to in...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Wang, Li, Rajamani, Jaya, Sommer, Marvin, Zerboni, Leigh, Arvin, Ann M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624212/
https://ncbi.nlm.nih.gov/pubmed/23345513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02963-12
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