Enterovirus 71 Infection Cleaves a Negative Regulator for Viral Internal Ribosomal Entry Site-Driven Translation

Far-upstream element-binding protein 2 (FBP2) is an internal ribosomal entry site (IRES) trans-acting factor (ITAF) that negatively regulates enterovirus 71 (EV71) translation. This study shows that EV71 infection cleaved FBP2. Live EV71 and the EV71 replicon (but not UV-inactivated virus particles)...

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Bibliographic Details
Main Authors: Chen, Li-Lien, Kung, Yu-An, Weng, Kuo-Feng, Lin, Jing-Yi, Horng, Jim-Tong, Shih, Shin-Ru
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624201/
https://ncbi.nlm.nih.gov/pubmed/23345520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02278-12
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