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The c-Myc-Regulated MicroRNA-17∼92 (miR-17∼92) and miR-106a∼363 Clusters Target hCYP19A1 and hGCM1 To Inhibit Human Trophoblast Differentiation

Mononuclear cytotrophoblasts of the human placenta proliferate rapidly, subsequently fuse, and differentiate to form multinucleated syncytiotrophoblast with induction of aromatase (hCYP19A1) and chorionic gonadotropin (hCGβ) expression. Using microarray analysis, we identified members of the miR-17∼...

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Detalhes bibliográficos
Main Authors: Kumar, Premlata, Luo, Yanmin, Tudela, Carmen, Alexander, James M., Mendelson, Carole R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624183/
https://ncbi.nlm.nih.gov/pubmed/23438603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01228-12
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