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The Drosophila Ortholog of MLL3 and MLL4, trithorax related, Functions as a Negative Regulator of Tissue Growth

The human MLL genes (MLL1 to MLL4) and their Drosophila orthologs, trithorax (trx) and trithorax related (trr), encode proteins capable of methylating histone H3 on lysine 4. MLL1 and MLL2 are most similar to trx, while MLL3 and MLL4 are more closely related to trr. Several MLL genes are mutated in...

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Detalhes bibliográficos
Main Authors: Kanda, Hiroshi, Nguyen, Alexander, Chen, Leslie, Okano, Hideyuki, Hariharan, Iswar K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624179/
https://ncbi.nlm.nih.gov/pubmed/23459941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01585-12
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