Reduced emotional signs of opiate withdrawal in rats selectively bred for low (LoS) versus high (HiS) saccharin intake

RATIONALE: Rats bred for high (HiS) and low (LoS) saccharin intake exhibit divergent behavioral responses to multiple drugs of abuse, with HiS rats displaying greater vulnerability to drug taking. Previous research indicates that this effect may be due to increased sensitivity to reward in HiS rats...

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Bibliographic Details
Main Authors: Radke, Anna K., Holtz, Nathan A., Gewirtz, Jonathan C., Carroll, Marilyn E.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624049/
https://ncbi.nlm.nih.gov/pubmed/23254375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-012-2945-0
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