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Metabolic Adaptation Follows Contractile Dysfunction in the Heart of Obese Zucker Rats Fed a High Fat “Western” Diet

The normal heart responds to changes in its metabolic milieu by changing relative oxidation rates of energy providing substrates. We hypothesized that this flexibility is lost when genetically obese rats are fed a high caloric, high fat ‘Western’ diet (WD). Male Zucker obese (ZO) and Zucker lean (ZL...

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Detalhes bibliográficos
Main Authors: Burgmaier, Mathias, Sen, Shiraj, Philip, Femi, Wilson, Christopher R., Miller, Charles C., Young, Martin E., Taegtmeyer, Heinrich
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623948/
https://ncbi.nlm.nih.gov/pubmed/20111021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oby.2009.500
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