Alcohol ingestion disrupts alveolar epithelial barrier function by activation of macrophage-derived transforming growth factor beta1

BACKGROUND: Chronic alcohol abuse causes oxidative stress and impairs alveolar epithelial barrier integrity, thereby rendering the lung susceptible to acute edematous injury. Experimentally, alcohol-induced oxidative stress increases the expression of transforming growth factor β1 (TGFβ1) in the lun...

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Hlavní autoři: Curry-McCoy, Tiana V, Venado, Aida, Guidot, David M, Joshi, Pratibha C
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623812/
https://ncbi.nlm.nih.gov/pubmed/23547562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-14-39
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