U1 small nuclear ribonucleoprotein particle-specific proteins interact with the first and second stem-loops of U1 RNA, with the A protein binding directly to the RNA independently of the 70K and Sm proteins.

The U1 small nuclear ribonucleoprotein particle (U1 snRNP), a cofactor in pre-mRNA splicing, contains three proteins, termed 70K, A, and C, that are not present in the other spliceosome-associated snRNPs. We studied the binding of the A and C proteins to U1 RNA, using a U1 snRNP reconstitution syste...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Patton, J R, Habets, W, van Venrooij, W J, Pederson, T
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1989
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362381/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2529425/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.8.3360-3368.1989
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