Lipid Droplet-Binding Protein TIP47 Regulates Hepatitis C Virus RNA Replication through Interaction with the Viral NS5A Protein

The nonstructural protein NS5A has emerged as a new drug target in antiviral therapies for Hepatitis C Virus (HCV) infection. NS5A is critically involved in viral RNA replication that takes place at newly formed membranes within the endoplasmic reticulum (membranous web) and assists viral assembly i...

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Главные авторы: Vogt, Dorothee A., Camus, Grégory, Herker, Eva, Webster, Brian R., Tsou, Chia-Lin, Greene, Warner C., Yen, Tien-Sze Benedict, Ott, Melanie
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623766/
https://ncbi.nlm.nih.gov/pubmed/23593007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003302
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