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A Comprehensive Profile of ChIP-Seq-Based STAT1 Target Genes Suggests the Complexity of STAT1-Mediated Gene Regulatory Mechanisms

Interferon-gamma (IFNγ) plays a key role in macrophage activation, T helper and regulatory cell differentiation, defense against intracellular pathogens, tissue remodeling, and tumor surveillance. The diverse biological functions of IFNγ are mediated by direct activation of signal transducer and act...

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Detalhes bibliográficos
Main Authors: Satoh, Jun-ichi, Tabunoki, Hiroko
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623615/
https://ncbi.nlm.nih.gov/pubmed/23645984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/GRSB.S11433
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