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A Single Electroporation Delivery of a DNA Vaccine Containing the Hemagglutinin Gene of Asian H5N1 Avian Influenza Virus Generated a Protective Antibody Response in Chickens against a North American Virus Strain

Protection against the avian influenza (AI) H5N1 virus is suspected to be mainly conferred by the presence of antibodies directed against the hemagglutinin (HA) protein of the virus. A single electroporation delivery of 100 or 250 μg of a DNA vaccine construct, pCAG-HA, carrying the HA gene of strai...

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Główni autorzy: Ogunremi, Oladele, Pasick, John, Kobinger, Gary P., Hannaman, Drew, Berhane, Yohannes, Clavijo, Alfonso, van Drunen Littel-van den Hurk, Sylvia
Format: Artigo
Język:Inglês
Wydane: American Society for Microbiology 2013
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Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623422/
https://ncbi.nlm.nih.gov/pubmed/23365205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00577-12
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