Genomic Sequencing Reveals Mutations Potentially Related to the Overattenuation of a Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus

Highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) continues to evolve when serially passaged in Marc-145 cells. In this study, we analyzed the genomic and antigenic variants of HP-PRRSV strain JXA1 during in vitro passage. Protective efficacies of JXA1 from passages 10...

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Detalhes bibliográficos
Main Authors: Yu, Xiuling, Chen, Nanhua, Deng, Xiaoyu, Cao, Zhen, Han, Wei, Hu, Dongmei, Wu, Jiajun, Zhang, Shuo, Wang, Baoyue, Gu, Xiaoxue, Tian, Kegong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Clinical Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623411/
https://ncbi.nlm.nih.gov/pubmed/23408525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00672-12
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