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Reduced Drug Uptake in Phenotypically Resistant Nutrient-Starved Nonreplicating Mycobacterium tuberculosis

During active tuberculosis a spectrum of physiologically different Mycobacterium tuberculosis bacilli reside in human tissues. Subpopulations of the pathogen survive antibiotic treatment for a prolonged time in a dormant state of phenotypic drug resistance, a phenomenon independent of genetic mutati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sarathy, Jansy, Dartois, Véronique, Dick, Thomas, Gengenbacher, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623341/
https://ncbi.nlm.nih.gov/pubmed/23335744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02202-12
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