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Bioengineering of Bacterial Polymer Inclusions Catalyzing the Synthesis of N-Acetylneuraminic Acid

N-Acetylneuraminic acid is produced by alkaline epimerization of N-acetylglucosamine to N-acetylmannosamine and then subsequent condensation with pyruvate catalyzed by free N-acetylneuraminic acid aldolase. The high-alkaline conditions of this process result in the degradation of reactants and produ...

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Autori principali: Hooks, David O., Blatchford, Paul A., Rehm, Bernd H. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623141/
https://ncbi.nlm.nih.gov/pubmed/23455347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03947-12
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