Pituitary Adenylate Cyclase 1 Receptor Internalization and Endosomal Signaling Mediate the Pituitary Adenylate Cyclase Activating Polypeptide-Induced Increase in Guinea Pig Cardiac Neuron Excitability

After G-protein-coupled receptor activation and signaling at the plasma membrane, the receptor complex is often rapidly internalized via endocytic vesicles for trafficking into various intracellular compartments and pathways. The formation of signaling endosomes is recognized as a mechanism that pro...

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Main Authors: Merriam, Laura A., Baran, Caitlin N., Girard, Beatrice M., Hardwick, Jean C., May, Victor, Parsons, Rodney L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623015/
https://ncbi.nlm.nih.gov/pubmed/23467377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4999-12.2013
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