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Mechanism of drug release from double-walled PDLLA(PLGA) microspheres

The drug release and degradation behavior of two double-walled microsphere formulations consisting of a doxorubicin loaded poly(D,L-lactic-co-glycolic acid) (PLGA) core (~46 kDa) surrounded by a poly(D,L-lactic acid) (PDLLA) shell layer (~55 and 116 kDa) were examined. It was postulated that differe...

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Bibliografiske detaljer
Main Authors: Xu, Qingxing, Chin, Shi En, Wang, Chi-Hwa, Pack, Daniel W.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622944/
https://ncbi.nlm.nih.gov/pubmed/23453059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.02.015
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