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Genetic Variation in BDNF is Associated with Antipsychotic Treatment Resistance in Patients with Schizophrenia

OBJECTIVE: Antipsychotic drugs are the mainstay of treatment for schizophrenia. However, a substantial proportion of patients are poorly responsive or resistant to first-line treatments, and clozapine treatment is often indicated. Therefore, we and others have used clozapine treatment as a proxy phe...

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Detalhes bibliográficos
Main Authors: Zhang, Jian-Ping, Lencz, Todd, Geisler, Stephen, DeRosse, Pamela, Bromet, Evelyn J., Malhotra, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622803/
https://ncbi.nlm.nih.gov/pubmed/23433505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2013.01.020
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