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Adipose tissue attracts and protects acute lymphoblastic leukemia cells from chemotherapy
Obesity is associated with an increased risk of acute lymphoblastic leukemia (ALL) relapse. Using mouse and cell co-culture models, we investigated whether adipose tissue attracts ALL to a protective microenvironment. Syngeneically implanted ALL cells migrated into adipose tissue within ten days. In...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3622767/ https://ncbi.nlm.nih.gov/pubmed/23332453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2012.12.013 |
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