Safety and maximum tolerated dose of superselective intraarterial cerebral infusion of bevacizumab after osmotic blood-brain barrier disruption for recurrent malignant glioma

OBJECT: The authors assessed the safety and maximum tolerated dose of superselective intraarterial cerebral infusion (SIACI) of bevacizumab after osmotic disruption of the blood-brain barrier (BBB) with mannitol in patients with recurrent malignant glioma. METHODS: A total of 30 patients with recurr...

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Detalhes bibliográficos
Main Authors: Boockvar, John A., Tsiouris, Apostolos J., Hofstetter, Christoph P., Kovanlikaya, Ilham I, Fralin, Sherese, Kesavabhotla, Kartik, Seedial, Stephen M., Pannullo, Susan C., Schwartz, Theodore H., Stieg, Philip, Zimmerman, Robert D., Knopman, Jared, Scheff, Ronald J., Christos, Paul, Vallabhajosula, Shankar, Riina, Howard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622705/
https://ncbi.nlm.nih.gov/pubmed/20964595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2010.9.JNS101223
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