Optogenetically Induced Seizure and the Longitudinal Hippocampal Network Dynamics

Epileptic seizure is a paroxysmal and self-limited phenomenon characterized by abnormal hypersynchrony of a large population of neurons. However, our current understanding of seizure dynamics is still limited. Here we propose a novel in vivo model of seizure-like afterdischarges using optogenetics,...

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Autori principali: Osawa, Shin-ichiro, Iwasaki, Masaki, Hosaka, Ryosuke, Matsuzaka, Yoshiya, Tomita, Hiroshi, Ishizuka, Toru, Sugano, Eriko, Okumura, Eiichi, Yawo, Hiromu, Nakasato, Nobukazu, Tominaga, Teiji, Mushiake, Hajime
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622611/
https://ncbi.nlm.nih.gov/pubmed/23593349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060928
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