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Identification of a pancreatic beta-cell insulin gene transcription factor that binds to and appears to activate cell-type-specific expression: its possible relationship to other cellular factors that bind to a common insulin gene sequence.

The insulin gene is expressed almost exclusively in pancreatic beta-cells. Previous work in our laboratory has shown that pancreatic beta-cell-specific expression of the rat insulin II gene is controlled by a number of positive and negative cis-acting DNA elements within the enhancer. We have shown...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: Whelan, J, Cordle, S R, Henderson, E, Weil, P A, Stein, R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 1990
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362261/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2181278/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.4.1564-1572.1990
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