Missense allele of a single nucleotide polymorphism rs2294008 attenuated antitumor effects of prostate stem cell antigen in gallbladder cancer cells

BACKGROUND: Prostate stem cell antigen (PSCA), an organ-dependent tumor suppressor, is down regulated in gallbladder cancer (GBC). It is anticipated that the missense allele C of the single nucleotide polymorphism (SNP) rs2294008 (T/C) in the translation initiation codon of the gene affects the gene...

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Bibliographische Detailangaben
Hauptverfasser: Ono, Hiroe, Chihara, Dai, Chiwaki, Fumiko, Yanagihara, Kazuyoshi, Sasaki, Hiroki, Sakamoto, Hiromi, Tanaka, Hideo, Yoshida, Teruhiko, Saeki, Norihisa, Matsuo, Keitaro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Medknow Publications & Media Pvt Ltd 2013
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622366/
https://ncbi.nlm.nih.gov/pubmed/23599686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1477-3163.109030
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