CYP2J2 overexpression increases EETs and protects against angiotensin II-induced abdominal aortic aneurysm in mice

Cytochrome P450 epoxygenase 2J2 (CYP2J2) metabolizes arachidonic acids to form epoxyeicosatrienoic acids (EETs), which possess various beneficial effects on the cardiovascular system. However, whether increasing EETs production by CYP2J2 overexpression in vivo could prevent abdominal aortic aneurysm...

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Detalhes bibliográficos
Principais autores: Cai, Zhejun, Zhao, Gang, Yan, Jiangtao, Liu, Wanjun, Feng, Wenjing, Ma, Ben, Yang, Lei, Wang, Jian-an, Tu, Ling, Wang, Dao Wen
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622337/
https://ncbi.nlm.nih.gov/pubmed/23446230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M036533
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