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Synergy Between Cell-Penetrating Peptides and Singlet Oxygen Generators Leads to Efficient Photolysis of Membranes

Cell-penetrating peptides such as TAT or R9 labeled with small organic fluorophores can lyse endosomes upon light irradiation. The photo-endosomolytic activity of these compounds can in turn be used to deliver proteins and nucleic acids to the cytosol of live cells with spatial and temporal control....

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Autori principali: Muthukrishnan, Nandhini, Johnson, Gregory A., Erazo-Oliveras, Alfredo, Pellois, Jean-Philippe
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622158/
https://ncbi.nlm.nih.gov/pubmed/23278754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/php.12036
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