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What do aquaporin knockout studies tell us about fluid transport in epithelia?

The investigation of near-isosmotic water transport in epithelia goes back over 100 years; however debates over mechanism and pathway still remain. Aquaporin (AQP) knockouts have been used by various research groups to test the hypothesis of an osmotic mechanism, as well as to explore the paracellul...

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Dettagli Bibliografici
Autori principali: Maclaren, Oliver J, Sneyd, James, Crampin, Edmund J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622118/
https://ncbi.nlm.nih.gov/pubmed/23430220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-013-9530-2
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