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Small Molecule Inhibitors of Hantavirus Infection

Hantaviruses use α(v)β(3) integrins on the surface of human host cells as a gateway to invasion, hence compounds that target this receptor may be used as antiviral agents. To accomplish this aim, new peptidomimetic compounds were selected based on similarity to a cyclic peptide known to bind the α(v...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hall, Pamela R., Leitão, Andrei, Ye, Chunyan, Kilpatrick, Kathleen, Hjelle, Brian, Oprea, Tudor I., Larson, Richard S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622053/
https://ncbi.nlm.nih.gov/pubmed/20951038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.09.092
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