Recurrent Exposure to Subclinical Lipopolysaccharide Increases Mortality and Induces Cardiac Fibrosis in Mice

BACKGROUND: Circulating subclinical lipopolysaccharide (LPS) occurs in health and disease. Ingesting high fatty meals increases LPS that cause metabolic endotoxemia. Subclinical LPS in periodontal disease may impair endothelial function. The heart may be targeted as cardiac cells express TLR4, the L...

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Huvudupphovsmän: Lew, Wilbur Y. W., Bayna, Evelyn, Molle, Erminia Dalle, Dalton, Nancy D., Lai, N. Chin, Bhargava, Valmik, Mendiola, Vincent, Clopton, Paul, Tang, Tong
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622013/
https://ncbi.nlm.nih.gov/pubmed/23585870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061057
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