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DNA Isolation Method Is a Source of Global DNA Methylation Variability Measured with LUMA. Experimental Analysis and a Systematic Review

In DNA methylation, methyl groups are covalently bound to CpG dinucleotides. However, the assumption that methyl groups are not lost during routine DNA extraction has not been empirically tested. To avoid nonbiological associations in DNA methylation studies, it is essential to account for potential...

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Detalhes bibliográficos
Main Authors: Soriano-Tárraga, Carolina, Jiménez-Conde, Jordi, Giralt-Steinhauer, Eva, Ois, Ángel, Rodríguez-Campello, Ana, Cuadrado-Godia, Elisa, Fernández-Cadenas, Israel, Montaner, Joan, Lucas, Gavin, Elosua, Roberto, Roquer, Jaume
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621987/
https://ncbi.nlm.nih.gov/pubmed/23585847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060750
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