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Protein Misfolding and Aggregation in Cataract Disease and Prospects for Prevention
The transparency of the eye lens depends on maintaining the native tertiary structures and solubility of the lens crystallin proteins over a lifetime. Cataract, the leading cause of blindness worldwide, is caused by protein aggregation within the protected lens environment. With age, covalent protei...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3621977/ https://ncbi.nlm.nih.gov/pubmed/22520268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2012.03.005 |
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