Requirement of Heterogeneous Nuclear Ribonucleoprotein C for BRCA Gene Expression and Homologous Recombination

BACKGROUND: Heterogeneous nuclear ribonucleoprotein C1/C2 (hnRNP C) is a core component of 40S ribonucleoprotein particles that bind pre-mRNAs and influence their processing, stability and export. Breast cancer tumor suppressors BRCA1, BRCA2 and PALB2 form a complex and play key roles in homologous...

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Détails bibliographiques
Auteurs principaux: Anantha, Rachel W., Alcivar, Allen L., Ma, Jianglin, Cai, Hong, Simhadri, Srilatha, Ule, Jernej, König, Julian, Xia, Bing
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621867/
https://ncbi.nlm.nih.gov/pubmed/23585894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061368
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